Shayn Peirce-Cottler headshot
SP

Shayn Peirce-Cottler

Professor
Unit: School of Medicine
Department: Department of Biomedical Engineering
Office location and address
Health System, Room 2324
415 Lane Rd
Charlottesville, Virginia 22903
Education
Ph.D., Biomedical Engineering, University of Virginia, 2002
Modeling to Design Treatments for Idiopathic Lung Fibrosis
Source: U.S. NIH Heart, Lung, And Blood Institute
July 01, 2021 – June 30, 2025
ZB131 Uses in Cancer
Source: ZielBio, Inc.
February 07, 2020 – December 31, 2022
EN-BME Multiscale Modeling for Treatment Discovery in Duchenne Muscular Dystrophy
Source: U.S. NIH Institute of Arthritis, Musculoskeletal &
September 09, 2016 – August 31, 2022
Modeling to Design Treatments for Vascular Pericyte Disassociation in Diabetes
Source: U.S. NIH Eye Institute
May 01, 2018 – April 30, 2022
11th World Congress for Microcirculation (WCM2018)
Source: U.S. NIH Heart, Lung, And Blood Institute
August 01, 2018 – July 31, 2019
MD-BIOM Bioengineering for the Therapeutic Delivery of Massively Expanded Islet-Derived Human Beta Cells
Source: Virginia Commonwealth University
May 01, 2017 – April 30, 2019
MD-BIOM Multiscale, Systems Modeling of Macrophage Infection YR03
Source: Leland Stanford Junior University
May 01, 2018 – April 30, 2019
MD-BIOM-In Vivo, single-cell analysis of recruited pericytes during angiogenesis and vessel stabilization
Source: American Heart Association
July 01, 2016 – June 30, 2018
MD-BIOM Multiscale, Systems Modeling of Macrophage Infection YR02
Source: Leland Stanford Junior University
May 01, 2017 – April 30, 2018
MD-INMD-CV modRNA VEGF-A effect on wound healing in leptin receptor deficient DB/DB mice
Source: AstraZeneca
January 15, 2016 – December 31, 2017
MD-BIOM Multiscale, Systems Modeling of Macrophage Infection
Source: Stanford University
May 01, 2016 – April 30, 2017
MD-BIOM Targeted Immunosuppression: A Novel Treatment for Uveitis-Induced Blindness in Children
Source: The Hartwell Foundation
April 01, 2014 – March 31, 2017
Adipose Stem Cells for Diabetic Retinopathy
Source: U.S. NIH Eye Institute
July 01, 2012 – June 30, 2016
MD-BIOM Walpole AHA Predoc Fellowship Role of Pericytes in Sprouting Angiogenesis
Source: American Heart Association - Mid-Atlantic Affiliat
July 01, 2013 – June 30, 2015
MD-BIOM Translational Research Partnership in Biomedical Engineering
Source: Wallace H. Coulter Foundation
December 01, 2005 – June 30, 2014
MD-BIOM NIDCR: "Therapeutic S1P Drug Targets"
Source: Georgia Institute Of Technology
August 24, 2012 – April 30, 2014
MD-BIOM Phospholipid Growth Factors for Therapeutic Arteriogenesis and Tissue Engineering
Source: Georgia Institute Of Technology
July 01, 2012 – August 09, 2013
MD-BIOM Arteriole/Venule Polarity in Adult Microvasculature
Source: U.S. NIH Heart, Lung, And Blood Institute
September 28, 2007 – July 31, 2013
BME 1501: Special Topics
Credits: 1
Student led special topic courses which vary by semester
ENGR 1501: Special Topics
Credits: 1
Student led special topic courses which vary by semester.
BME 4550: Special Topics in Biomedical Engineering
Credits: 3
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation. Prerequisite: third- or fourth-year standing and instructor permission.
BME 4995: Biomedical Engineering Advanced Projects
Credits: 1–3
A year-long research project in biomedical engineering conducted in consultation with a department faculty advisor; usually related to ongoing faculty research. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Requires a comprehensive report of the results. Prerequisite: third- or fourth-year standing, and instructor permission.
BME 6101: Physiology I for Engineers
Credits: 3
Introduces fundamental concepts of cellular physiology; applies quantitative engineering analysis to intra- and intercellular signaling and mechanical systems relevant to organ physiology and pathology; teaches students to learn to think critically about the physiology and cell biology literature. Prerequisite: BME 2104 or equivalent; proficiency with ODEs.
BME 6311: BME Measurement Principles
Credits: 3
Students will gain a fundamental understanding of the theoretical principles underlying biomedical measurements. Topics are organized sequentially from signal initiation through signal processing to downstream statistical analysis of measurements. Students will be exposed to the practical implementation of general principles through homework assignments that involve the analysis and evaluation of molecular, cellular, and clinical measurements. Prerequisites: 1. BME 6101: Physiology I (or equivalent) 2. SEAS graduate student status 3. Some previous exposure to probability-statistics, Fourier analysis, and linear systems 4. Or Instructor Permission
BME 6315: Systems Bioengineering
Credits: 3
Introduces techniques for constructing mathematical and computational models of biological processes at many levels of organizational scale from genome to whole-tissue. Topics include choice of techniques, quantitative characterization of biological properties, assumptions and model simplification, parameter estimation and sensitivity analysis, model verification and validation and integration of computational modeling w/experimental approaches. Prerequisites: BME 6101, and BME 2104 or BME 7806 (or equivalent).
BME 8315: Systems Bioengineering and Multi-Scale Models
Credits: 3
In this course students will gain working knowledge of constructing mathematical and computational models of biological processes at many levels of organizational scale from genome to whole-tissue. Students will rotate through several modules where they will hear lectures, read literature, and participate in discussions focused on the various modeling techniques. Prerequisites: BME 6101/6102: Physiology (or equivalent); 2. One of the following courses in cellular and/or molecular biology: BME 2104: Cell and Molecular Biology for Engineers, BME 7806: Genetic Engineer.
BME 8900: Graduate Teaching Instruction
Credits: 1–12
For master's students.
BME 8995: M.E. Supervised Project Research (M.E. STUDENTS ONLY)
Credits: 1–6
FOR M.E. STUDENTS ONLY. A research project in biomedical engineering conducted in consultation with a faculty advisor. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Fulfills the project requirement for the Biomedical Engineering Masters of Engineering degree. Prerequisites: Instructor Permission Required.
BME 8999: Master's Research
Credits: 1–12
Master's Research
PATH 9995: Topical Research
Credits: 1–12
Original research on approved problems.
BME 9999: Dissertation
Credits: 1–12
Formal record of student commitment to doctoral research under the guidance of a faculty advisor. May be repeated as necessary.
PATH 9999: Non-Topical Research
Credits: 1–12
Dissertation research credit for students who have completed their advancement to candidacy.