Mark Okusa headshot
MO

Mark D. Okusa

Professor
Unit: School of Medicine
Department: Department of Medicine, Nephrology Division
Office location and address
Kidney Center Clinic
1335 Lee St
Charlottesville, Virginia 22903
Education
MD, Medical College of Virginia
Fellowship, Yale School of Medicine
Residency, Medical College of Virginia, VCU, Richmond, VA
Biography

Mark D. Okusa, M.D. is the John C. Buchanan Distinguished Professor of Medicine, Chief, Division of Nephrology and Director, Center for Immunity, Inflammation and Regenerative Medicine at the University of Virginia, Charlottesville, VA. He received his M.D., and internship and residency training at the Medical College of Virginia, Richmond, VA followed by clinical and research nephrology training at Yale University, New Haven, CT. Dr. Okusa was recruited to the University of Virginia in 1991 as a clinician investigator combining clinical care, education and research. His clinical interests include acute and chronic kidney injury.  He participates in care of patients by maintaining Nephrology Clinic, attending on a general medicine ward, and attending on the nephrology consult service.  Current research involves the role of inflammation and immune cells in initiating and maintaining acute kidney injury. Through funding from the National Institutes of Health he has developed the foundation for clinical trials using adenosine 2a agonists and lysophospholipid ligands in both acute kidney injury as well as in diabetic nephropathy. He is the principal investigator of several NIH grants including a T32 training grant "Kidney Disease and Inflammation".  He has published over 70 original manuscripts and book chapters. At the national level Dr. Okusa has established himself in the area of acute kidney injury.  He is the Chair of the Acute Kidney Injury Advisory Committee of the American Society of Nephrology (ASN) and member of the Acute Kidney Injury Network and ASN Grants Committee. Dr. Okusa served on the ASN Program Committee (2007) and the NIH Pathobiology of Kidney Disease Study Section (2004-2008) and was recently selected to Chair the Scientific Program of the American Society of Nephrology (2011). Dr. Okusa has been a visiting professor at a number of institutions and served as a plenary speaker at various national and international meetings. Dr. Okusa is an Associate Editor of Nephron Physiology, and member of the editorial board of the American Journal of Physiology:Renal Physiology, American Journal of Nephrology and Kidney International. Dr. Okusa has been listed in Castle Connally's America's Top Doctors (2001-2010) and Best Doctors in America (2005-2010).

Dr. Okusa's interest outside of work include long distance running and playing the classical guitar.

The University of Virginia Kidney Technology Development Research Education Program (VA K-TUTOR)
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
April 01, 2020 – January 31, 2025
Neuroimmune Regulation of Acute Kidney Injury
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
September 19, 2019 – July 31, 2024
Sphingolipids in Acute Kidney Injury and Disease Progression
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
April 01, 2020 – March 31, 2024
MD-INMD-NEPH Kidney Disease and Inflammation
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
August 01, 2016 – June 30, 2022
Integrated Virginia Research Training Centers in KUH (IGNITE KUH)
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
September 16, 2021 – May 31, 2022
MD-INMD Nephrology Visiting Professor and Invited Speaker Exchange Program GDE# GDE11.22.13uva
Source: The Bower Foundation
December 15, 2013 – May 15, 2022
MD-INMD Ultrasound for Non-Invasive Prevention of Acute Kidney Injury
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
September 21, 2015 – July 31, 2021
Pannexin 1 and Acute Kidney Injury
Source: American Society Of Nephrology
July 01, 2019 – June 30, 2021
MD-INMD-NE Sphingolipids in Acute Kidney Injury and Disease Progression
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
July 01, 2015 – March 31, 2020
MD-INMD-NE Am-Pharma MODE Of ACTION OF RECAP IN RENAL MOUSE MODE
Source: Pfizer Inc.
March 21, 2016 – November 20, 2019
MD-INMD Tailoring Ultrasound Technology to explore mechanisms of actiation of the splenic neuroimmune axis in attenuating acute organ injury
Source: U.S. NIH Institute of Biomedical Imaging & Bioengi
September 30, 2015 – January 31, 2019
Research for the Mechanism of the Inflammatory Reflex with Optogenetics
Source: The Uehara Memorial Foundation
January 01, 2018 – December 31, 2018
Medical Education Grant - Renal Grand Rounds
Source: Relypsa, Inc.
February 28, 2018 – November 30, 2018
MD-INMD-NE Leukocyte Trafficking in Acute Renal Failure
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
December 01, 2012 – November 30, 2017
MD-INMD-NE-HP8W Endothelial Sphingosine-1-phosphate receptor 1 regulates renal recovery for after acute kidney injury
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
September 30, 2015 – September 29, 2017
Kidney Disease and Inflammation
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
August 01, 2011 – December 31, 2016
MD-INMD-NE Endothelial S1P1 is Necessary for Recovery from IRI and Protects Against Development of Fibsrosis
Source: American Society Of Nephrology
July 01, 2015 – June 01, 2016
Leukocyte Trafficking in Acute Renal Failure
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
December 01, 2012 – November 30, 2015
Naturally Occurring IgM Anti-Leucocyte Autoantibodies Protect Against Renal IRI
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
March 12, 2010 – August 31, 2015
MD-INMD Improvement of Sphingosine Kinase-2 Inhibitors
Source: SphynKx Therapeutics, LLC
April 01, 2014 – June 14, 2015
Nanotherapeutics for acute kidney injury
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
April 26, 2012 – March 31, 2015
Sphingolipids in Acute Kidney Injury
Source: U.S. NIH Institute of Diabetes & Digestive & Kidne
March 15, 2010 – March 14, 2015
MD-INMD Evaluation of Sphingosine Kinase Inhibitors for the Treatment of Chronic Kidney Disease
Source: SphynKx Therapeutics, LLC
August 14, 2013 – October 31, 2014
BIMS 8993: Non-topical Research: Visiting Research Graduate Traineeship Program
Credits: 1–12
This course is for visiting research students participating in the BIMS Visiting Research Graduate Trianeeship Program (VRGTP). Students in this course are dual enrolled in their home institution and will participate in research for a minimum of 4 semesters. The research will assist them in completing their degree at their home institution. Non-degree students.
PHY 9998: Non-Topical Research, Preparation for Doctoral Research
Credits: 1–12
For doctoral research, taken before a dissertation director has been selected.
PATH 9999: Non-Topical Research
Credits: 1–12
Dissertation research credit for students who have completed their advancement to candidacy.
PHY 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation.
BIMS 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation following advancement to PhD candidacy.
BIOP 9999: Non-Topical Research
Credits: 1–12
For doctoral research, taken under the supervision of a dissertation director.
  • 2015-2018 Best Doctors in America® List