Jeffrey Smith headshot
JS

Jeffrey S. Smith

Professor
Unit: School of Medicine
Department: Department of Biochemistry and Molecular Genetics
Office location and address
1340 Jefferson Park Ave
Charlottesville, Virginia 22903
Education
BS, LIU/ Southampton Campus, Southampton, NY
PhD, University of Medicine and Dentistry/ RWJMS
Postdoc, Johns Hopkins School of Medicine
Targeting RNA Polymerase I Transcription Machinery in Chemoresistant Ovarian Cancer
Source: U.S. NIH Cancer Institute
March 01, 2020 – February 28, 2025
Aging-induced nucleolar decline and chromosomal instability
Source: U.S. NIH Institute of General Medical Science
August 01, 2020 – June 30, 2024
Caloric Restriction directs topological chromatin reorganization fellowship on behalf of Elisa Enriquez Hesles
Source: U.S. NIH Institute on Aging
September 01, 2020 – August 31, 2023
Control of mating-type switching by Sir2 and condensin
Source: U.S. NIH Institute of General Medical Science
August 13, 2018 – April 30, 2022
Long non-coding RNAs as novel therapeutic targets in gliomas treatment
Source: U.S. NIH Cancer Institute
August 01, 2020 – June 30, 2021
Trans-Kingdom Longevity Factors Derived from Budding Yeast
Source: U.S. NIH Institute on Aging
September 15, 2017 – January 31, 2020
MD-BIOC NAD and the Regulation of Sirtuin Targets
Source: U.S. NIH Institute of General Medical Science
April 01, 2014 – December 31, 2018
MD-BIOC Functional Sir2-RNA Interactions
Source: U.S. NIH Institute on Aging
April 01, 2013 – March 31, 2016
An epigenetic approach to sex differences
Source: U.S. NSF - Directorate For Biological Sciences
April 01, 2011 – March 31, 2016
NAD Biosynthesis and the Regulation of Sirtuins
Source: U.S. NIH Institute of General Medical Science
September 30, 2009 – August 31, 2013
BIOC 8012: Chromatin I
Credits: 2
The Chromatin course modules are designed to provide students with an in-depth understanding of chromatin structure and function. In Chromatin I, the focus will be on chromatin structure and organization, nucleosome and chromatin remodeling factors, and the multiple histone modifying enzymes that regulate DNA-templated cellular functions such as transcription, DNA replication, and repair.
BIOC 8014: Chromatin II
Credits: 2
The Chromatin course modules are designed to provide students with an in-depth understanding of chromatin structure and function. Chromatin II will focus on the functional aspects of chromatin organization and regulation. The course will meet two days a week, with time split between faculty presentations that introduce a topic and provide key information, and more interactive sessions that will involve discussions of primary literature. Prerequisite: Restricted to BIMS students or departmental approval required
BIOC 8130: Colloquium
Credits: 1
Research seminars by invited guests and research personnel within the department. All biochemistry graduate students must attend.
BIOC 8131: Colloquium
Credits: 1
Research seminars by invited guests and research personnel within the department. All biochemistry graduate students must attend.
BIMS 8993: Non-topical Research: Visiting Research Graduate Traineeship Program
Credits: 1–12
This course is for visiting research students participating in the BIMS Visiting Research Graduate Trianeeship Program (VRGTP). Students in this course are dual enrolled in their home institution and will participate in research for a minimum of 4 semesters. The research will assist them in completing their degree at their home institution. Non-degree students.
BIMS 8995: Topical Research: Research in Biomedical Sciences
Credits: 1–12
This course introduces students to biomedical research. Students conduct one or more research projects of limited scope under the direction of faculty and lab members. It is open only to graduate students in Biomedical Sciences (BIMS).
BIOC 9995: Topical Research: Biochemistry and Molecular Genetics
Credits: 3–12
Topical Research
BIOC 9998: Non-Topical Research: Preparation for Doctoral Research
Credits: 1–12
Non-Topical Research: Preparation for Doctoral Research
BIMS 9998: Non-Topical Research
Credits: 1–12
Preparation for Doctoral Research prior to completion of candidacy examination.
BIOC 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation, taken under the supervision of a dissertation director.