JS
Unit: School of Medicine
Department: Department of Biomedical Engineering
Office location and address
415 Lane Rd
Charlottesville,
Virginia
22903
Education
PhD, University of California at San Diego
Publications
Sponsored Awards
MD-BIOM Systems Pharmacology Model for Spatial Control of Cardiac Fibrosis
Source: U.S. NIH Heart, Lung, And Blood Institute
July 01, 2017 – June 30, 2022
Systems biology approaches to identify therapeutic targets in cardiac fibroblast signaling post myocardial infarction - Pre-Doctoral Fellowship for Mukti Chowkwale
Source: American Heart Association
April 01, 2021 – March 31, 2022
MD-INMD AZ Master Agreement
Source: AstraZeneca
December 08, 2009 – December 31, 2021
MD-INMD CVRC Master Research Collaboration Agreement
Source: AstraZeneca
October 01, 2016 – December 31, 2021
System Biology of Hypertrophic Heart Disease
Source: University of California, San Diego
February 13, 2017 – July 31, 2021
MD-BIOM Differential regulation of hypertrophy and apoptosis by beta adrenergic signaling in cardiac myocytes - Fellowship on behalf of Bryan Chun
Source: U.S. NIH Heart, Lung, And Blood Institute
September 01, 2016 – November 30, 2020
MD-BIOM Modeling Cardiac Fibroblast Signaling to Predict Context-Dependent Modulators of Cardiac Fibrosis - Fellowship on behalf of Angela Zeigler
Source: U.S. NIH Heart, Lung, And Blood Institute
September 01, 2016 – May 31, 2020
MD-BIOM CAREER: Systems analysis of the cardiac hypertrophy signaling network
Source: U.S. NSF - Directorate For Engineering
April 01, 2013 – March 31, 2019
MD-BIOM-UMMC sub Systems Biology of Macrophage Polarization Following Myocardial Infarction
Source: University of Mississippi Medical Center
November 01, 2015 – December 31, 2018
MD-BIOM Logical network modeling to mechanistically integrate omic and phenotypic signatures
Source: Icahn School of Medicine at Mount Sinai
May 01, 2017 – April 30, 2018
MD-BIOM CaMKII multiscale model subcontract
Source: University of California, San Diego
March 01, 2012 – February 28, 2018
MD-BIOM Logical network modeling to mechanistically integrate omic and phenotypic signatures
Source: Icahn School of Medicine at Mount Sinai
May 01, 2016 – April 30, 2017
MD-BIOM CLOSED
Source: University of California, San Diego
February 13, 2017 – February 13, 2017
Modeling Fibroblast Signaling to Predict Context-Dependent Modulators of Cardiac Fibrosis_CLOSED
Source: American Heart Association
July 01, 2016 – October 03, 2016
CDI-Type I: Accelerating SImulations Using CPU+FPGA Heterogeneous Processing
Source: U.S. NSF - Directorate Computer & Info. Sciences
September 15, 2011 – August 31, 2016
Quantitative Analysis of cAMP Compartmentation in Heart
Source: U.S. NIH Heart, Lung, And Blood Institute
September 01, 2011 – June 30, 2015
Courses
Credits: 3
Introduces computational techniques for solving biomedical engineering problems & constructing models of biologic processes. Numerical techniques include regression, interpolation, differentiation, integration, root finding, systems of equations, optimization and approaches to ordinary differential equations. Applications include bioreactors, biotransport, pharmacokinetics & biomechanics. Prereq: APMA 2120 & CS 1110; recommended co-req APMA 2130.
Credits: 3
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation. Prerequisite: third- or fourth-year standing and instructor permission.
Credits: 1–3
A year-long research project in biomedical engineering conducted in consultation with a department faculty advisor; usually related to ongoing faculty research. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Requires a comprehensive report of the results. Prerequisite: third- or fourth-year standing, and instructor permission.
Credits: 3
Introduces techniques for constructing mathematical and computational models of biological processes at many levels of organizational scale from genome to whole-tissue. Topics include choice of techniques, quantitative characterization of biological properties, assumptions and model simplification, parameter estimation and sensitivity analysis, model verification and validation and integration of computational modeling w/experimental approaches. Prerequisites: BME 6101, and BME 2104 or BME 7806 (or equivalent).
Credits: 3
In this course students will gain working knowledge of constructing mathematical and computational models of biological processes at many levels of organizational scale from genome to whole-tissue. Students will rotate through several modules where they will hear lectures, read literature, and participate in discussions focused on the various modeling techniques. Prerequisites: BME 6101/6102: Physiology (or equivalent); 2. One of the following courses in cellular and/or molecular biology: BME 2104: Cell and Molecular Biology for Engineers, BME 7806: Genetic Engineer.
Credits: 1–6
FOR M.E. STUDENTS ONLY. A research project in biomedical engineering conducted in consultation with a faculty advisor. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Fulfills the project requirement for the Biomedical Engineering Masters of Engineering degree. Prerequisites: Instructor Permission Required.
Credits: 1–12
Master's Research
Credits: 1–12
Original research on approved problems.
Credits: 1–12
For doctoral dissertation, taken under the supervision of a dissertation director.
Credits: 1–12
Formal record of student commitment to doctoral research under the guidance of a faculty advisor. May be repeated as necessary.