John Bushweller headshot
JB

John H. Bushweller

Professor
Unit: School of Medicine
Department: Department of Molecular Phys and Biological Physics
Office location and address
480 Ray C. Hunt Dr
Charlottesville, Virginia 22903
Education
BA, Dartmouth College
PhD, University of California, Berkeley, CA
Postdoc, Eidgenössische Technische Hochschule, Zürich, Switzerland
AF9(MLLT3) function in leukemia and normal hematopoiesis
Source: U.S. NIH Cancer Institute
July 01, 2019 – June 30, 2024
Targeted Small Molecule Inhibitors for Inv(16) Leukemia
Source: U.S. NIH Cancer Institute
December 01, 2018 – November 30, 2023
The Center for Therapeutic Targeting of EWS-oncoproteins - Year 4
Source: Dana-Farber Cancer Institute, Inc.
July 01, 2021 – January 01, 2022
Virginia Kincaid Cancer Research Fund
Source: Virginia Kincaid Charitable Trust
October 01, 2005 – December 31, 2021
RUNX1-ETO targeted small molecule therapy for t(8;21) acute myeloid leukemia
Source: Leukemia & Lymphoma Society
December 31, 2019 – September 29, 2021
Small Molecule Inhibitors of a Reader of DNA Methylation
Source: U.S. NIH Cancer Institute
July 01, 2019 – June 30, 2021
The Center for Therapeutic Targeting of EWS-oncoproteins - Year 3
Source: Dana-Farber Cancer Institute, Inc.
July 01, 2020 – June 30, 2021
The Center for Therapeutic Targeting of EWS-oncoproteins - Year 2
Source: Dana-Farber Cancer Institute, Inc.
July 01, 2019 – June 30, 2020
The Center for Therapeutic Targeting of EWS-oncoproteins
Source: Dana-Farber Cancer Institute, Inc.
September 10, 2018 – June 30, 2019
American Society of Hematology Bridge Grant
Source: American Society Of Hematology
July 01, 2017 – June 30, 2018
Structure/Function of AF9 and MLL-AF9
Source: U.S. NIH Cancer Institute
August 03, 2011 – June 30, 2017
MD-MPHY Small Molecule Inhibitors of ERG for Pediatric Leukemia and Sarcoma
Source: Alex's Lemonade Stand Foundation for Childhood Can
July 01, 2015 – June 30, 2017
MD-MPHY Screening for Inhibitors of Myb Function as Potential Therapeutic Approach to Adenoid Cystic Carcinoma
Source: Adenoid Cystic Carcinoma Research Foundation
January 01, 2014 – December 31, 2016
MD-MPHY ALS-POST-Dalrymple-Bushweller-Identification and Characterization of Selective MLL1 CXXC Domain Inhibitors
Source: Alex's Lemonade Stand Foundation for Childhood Can
June 27, 2016 – August 22, 2016
Structural Biology of AML (CBFA2) & AML1-ETO
Source: U.S. NIH Cancer Institute
May 25, 2010 – March 31, 2016
Development of Novel Therapeutic Approaches to MLL Fusion Leukemia
Source: William Lawrence & Blanche Hughes Foundation
December 15, 2010 – November 30, 2015
Solution NMR Structure and Function of the Integral Membrane Protein DsbB
Source: U.S. NIH Institute of General Medical Science
September 01, 2010 – August 30, 2015
Development of Inhibitors of the Leukemia Fusion Protein CBFbeta-SMMHC
Source: U.S. NIH Cancer Institute
May 10, 2010 – March 31, 2015
Predoctoral Fellowship on Behalf of Aravinda Kuntimaddi
Source: American Heart Association - Mid-Atlantic Affiliat
July 01, 2012 – June 30, 2014
Training in Molecular Biophysics
Source: U.S. NIH Institute of General Medical Science
July 01, 2008 – June 30, 2013
BIOP 8030: Magnetic Resonance Spectroscopy of Macromolecules I
Credits: 2
Exploration of magnetic resonance spectroscopy as it is applied to biopolymers. The first module will cover principles of nuclear magnetic resonance (NMR) will be covered, including basic principles, homonuclear and heteronuclear NMR methods. Prerequisite: BIOP 8201/8301, Biophysical Principles
BIOP 8031: Magnetic Resonance Spectroscopy of Macromolecules II
Credits: 2
Exploration of magnetic resonance spectroscopy as it is applied to biopolymers. Data collection for structure determination, residual dipolar couplings, approaches to large systems, and the use of NMR to deduce information about the dynamic behavior of proteins will be covered. Finally, principles of electron paramagnetic resonance spectroscopy will be presented. Prerequisite: BIOP 8030, Magnetic Resonance Spectroscopy of Macromolecules I
BIMS 8993: Non-topical Research: Visiting Research Graduate Traineeship Program
Credits: 1–12
This course is for visiting research students participating in the BIMS Visiting Research Graduate Trianeeship Program (VRGTP). Students in this course are dual enrolled in their home institution and will participate in research for a minimum of 4 semesters. The research will assist them in completing their degree at their home institution. Non-degree students.
CHEM 9420: Research in Chemical and Structural Biology
Credits: 1–12
Research in Chemical and Structural Biology
BIOP 9995: Biophysics Research
Credits: 3–12
Independent study, other than non-topical research, for course credits.
BIOC 9995: Topical Research: Biochemistry and Molecular Genetics
Credits: 3–12
Topical Research
BIOC 9998: Non-Topical Research: Preparation for Doctoral Research
Credits: 1–12
Non-Topical Research: Preparation for Doctoral Research
BIOC 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation, taken under the supervision of a dissertation director.
BIOP 9999: Non-Topical Research
Credits: 1–12
For doctoral research, taken under the supervision of a dissertation director.