Hong-Ru Chen

Assistant Professor
Unit: School of Medicine
Department: Department of Neuroscience
Office location and address
MR-4, 4022
409 Lane Rd
Charlottesville, Virginia 22903
Ph.D., National Yang-Ming University, Taipei, Taiwan, 2015
Trainee, Marine Biological Laboratory, MA, USA, 2014

Dr. Chen's primary research interest is to investigate how neurons and monocyte-derived pathological microglia interact to mediate neural physiology and behavior in various neurological conditions, towards the development of immune-targeted therapies of the disease condition. The diseases that she studies include maternal immune activation, neonatal hypoxia-ischemia (HI), infection-sensitized HI, and neonatal stroke. Her second research interest is the developmental effect of infection-sensitized HI in offspring. This is because Autism Spectrum Disorder (ASD) has diverse etiologies due to complex interactions of genetic, immune, and environmental risk factors, including birth asphyxia/hypoxia-ischemia (HI). To test this idea, she has developed a two-hit model of neurodevelopmental defects by subjecting the offspring of murine maternal immune activation (MIA) under a moderate Rice-Vannucci HI insult to produce autistic-like behaviors and synaptic defects.


               Two-years postdoctoral fellowship, American Heart Association (AHA), USA (#18POST34080334) 

2019      Award of second place for postdoctoral poster presentation, Central Virginia Chapter of the Society for Neuroscience, USA 

2018      Traveling award of the Society for Neuroscience (SfN), USA 

2018      Award of first place for postdoctoral poster presentation, Central Virginia Chapter of the Society for Neuroscience, USA 

2015      Award of first prize in oral presentation, International Conference on Stem Cells and Developmental Biology, Taiwan 

2014      The outstanding student paper awards, National Yang-Ming University, Taiwan 

2014      Scholarship award offered by the C. Lalor Burdick Scholarship Society for Developmental Biology, USA 

2013      Award of honored poster presentation of the Neuroscience Society of Taiwan 

2012, 2013, 2014, 2015      

               Award of excellent poster presentation in Graduate Students Poster Exhibition, National Yang-Ming.  University, Taiwan 

2010, 2011, 2012     

               Excellent teaching award, National Yang-Ming University, Taiwan 

2010      Award of honored poster presentation in Graduate Students Poster Exhibition, National Yang-Ming University, Taiwan 

2010, 2013   

                Grants for attending international conferences of National Science Council, Taiwan