Brant Isakson headshot
BI

Brant Isakson

Professor
Unit: School of Medicine
Department: Department of Molecular Phys and Biological Physics
Office location and address
409 Lane Rd
Charlottesville, Virginia 22903
Education
PhD, University of Wyoming
Pannexin Channels in Vascular Physiology and Inflammation Years 6-10
Source: U.S. NIH Heart, Lung, And Blood Institute
June 01, 2019 – May 31, 2024
Myoendothelial junctions as regulators of endothelial barrier integrity
Source: U.S. NIH Heart, Lung, And Blood Institute
September 01, 2019 – August 31, 2022
Conference Funding for International Symposium on Resistance Arteries (ISRA) 2020
Source: U.S. NIH Heart, Lung, And Blood Institute
July 01, 2020 – June 30, 2022
Purinergic Regulation of Veinous Endothelial Permeability
Source: U.S. National Institutes of Health (NIH)
February 18, 2018 – January 31, 2022
Pannexin 3 channels in endothelial-derived vasodilation
Source: U.S. NIH Heart, Lung, And Blood Institute
August 01, 2019 – July 31, 2021
Targeting Vascular Leak-induced Nanodomain Dysfunction to Treat Atrial Fibrillation
Source: OHIO STATE UNIVERSITY
July 01, 2020 – June 30, 2021
UFL-Pannexin-1 signaling in Abdominal Aortic Aneurysms
Source: University Of Florida
July 09, 2018 – June 30, 2021
Endothelial Hemoglobin Alpha Regulates Vasodilation in Response to Exercise
Source: U.S. NIH Heart, Lung, And Blood Institute
July 01, 2018 – June 30, 2020
Vascular Pannexin 1 in Ischemic Stroke
Source: U.S. NIH Heart, Lung, And Blood Institute
August 15, 2018 – March 31, 2020
The role of endothelial cells in the pathology of Zika Virus infection
Source: U.S. National Academy Of Sciences
September 01, 2018 – August 31, 2019
Disruption of the alpha globin/eNOS complex in the endothelium
Source: U.S. NIH Heart, Lung, And Blood Institute
July 01, 2018 – August 30, 2019
MD-MICR-KR Pannexin Channels in Vascular Physiology and Inflammation
Source: U.S. NIH Heart, Lung, And Blood Institute
August 01, 2014 – May 31, 2019
MD-CVRC Mechanisms of Heterocellular Signaling at the Myoendothelial Junction
Source: U.S. NIH Heart, Lung, And Blood Institute
April 01, 2014 – March 31, 2019
Alpha-a-Adrenergic Pannexiin 1 Activation is Mediated by Src Family Kinases; Fellowhip on behalf of Leon Delalio
Source: U.S. NIH Heart, Lung, And Blood Institute
April 01, 2017 – November 30, 2018
MD-CVRC-Mechanisms of ATP release from Pannexin 1 in Red Blood Cells in Response to Hypoxia
Source: American Heart Association
July 01, 2016 – June 30, 2018
MD-CVRC-Increasing NO Via an Alpha Globin Mimetic Peptide as Treatment for Sickle Cell Induced Pulmonary Hypertension
Source: American Heart Association
July 01, 2016 – June 30, 2018
MD-CVRC Pannexin 1 Channels in Cerebral Arterial Myogenic Regulation - Fellowship on behalf of Miranda Good
Source: U.S. NIH Heart, Lung, And Blood Institute
July 01, 2016 – September 30, 2017
MD-CVRC Calreticulin as a Regulator of Endothelial and Smooth Muscle Cell Communication
Source: American Heart Association - Mid-Atlantic Affiliat
July 01, 2014 – June 30, 2016
MD-CVRC Endothelial Hba Regulates Blood Pressure
Source: American Heart Association
July 01, 2015 – October 01, 2015
MD-CVRC Regulation of pannexinl channels by Nitric oxide
Source: American Heart Association - Mid-Atlantic Affiliat
July 01, 2012 – June 30, 2014
MD-CVRC Mechanisms of Heterocellular Signaling at the Myoendothelial Junction
Source: U.S. NIH Heart, Lung, And Blood Institute
January 01, 2008 – March 31, 2014
Mechanism of Plasminogen Activator Inhibitor-1 Polarization to Myoendothelial Jun
Source: U.S. NIH Heart, Lung, And Blood Institute
January 15, 2012 – December 31, 2013
Career on Behalf of Adam Straub
Source: U.S. NIH Heart, Lung, And Blood Institute
June 15, 2012 – May 31, 2013
PHY 8040: Physiology A
Credits: 2
The course will integrate background cellular and molecular knowledge into organ systems and whole animal, function. It is intended to provide the ability to integrate knowledge at the molecular level into function, the foundation of translational-based research. The physiology to be covered will include the nervous system, metabolism and endocrine systems.
PHY 8041: Physiology B
Credits: 2
The course will integrate background cellular and molecular knowledge into organ systems and whole animal, function. It is intended to provide the ability to integrate knowledge at the molecular level into function the foundation of translational-based research. Specifically, the physiology to be covered will include the heart, vasculature, kidney, GI, and muscle. Requisites: PHY 8040 or permission of instructor
PHY 8052: Vascular Biology A
Credits: 2
The class covers the broad range of vascular biology from the basic science to clinical implications. The class integrates new methods in the field and relationships to heart function. Prerequisite: PHY 8040
PHY 8053: Vascular Biology B
Credits: 2
The class covers the broad range of vascular biology from the basic sciences to the clinical implications. In addition, the class integrates new methods in the field and relationships to heart function. Prerequisite: PHY 8040 and PHY 8052
PHY 8100: Extreme Physiology
Credits: 2
The course focuses on aspects of human physiology observed during extreme environmental conditions. This includes: effects of gravity (e.g., space) on human physiology; effects of marathon running on human physiology, as well as high altitude and deep sea diving. These extremes will be discussed with an eye towards better understanding homeostatic and pathological human physiology.
BIMS 8995: Topical Research: Research in Biomedical Sciences
Credits: 1–12
This course introduces students to biomedical research. Students conduct one or more research projects of limited scope under the direction of faculty and lab members. It is open only to graduate students in Biomedical Sciences (BIMS).
BME 8999: Master's Research
Credits: 1–12
Master's Research
PHAR 9995: Research in Pharmacology
Credits: 1–12
Original research on approved problems.
PHY 9995: Research
Credits: 3–12
Directed research on an approved problem in physiology.
BIMS 9998: Non-Topical Research
Credits: 1–12
Preparation for Doctoral Research prior to completion of candidacy examination.
PHY 9998: Non-Topical Research, Preparation for Doctoral Research
Credits: 1–12
For doctoral research, taken before a dissertation director has been selected.
CELL 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation, taken under the supervision of a dissertation director.
PHY 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation.
BME 9999: Dissertation
Credits: 1–12
Formal record of student commitment to doctoral research under the guidance of a faculty advisor. May be repeated as necessary.
PHAR 9999: Non-Topical Research
Credits: 1–12
For doctoral dissertation, taken under the supervision of a dissertation director.