Ammasi Periasamy headshot
AP

Ammasi Periasamy

Professor
Center Director, WM Keck Center for Cellular Imaging
Unit: College of Arts and Sciences
Department: Department of Biology
Office location and address
B005 PLSB
90 Geldard Driv
Charlottesville, Virginia 22903
Education
B.S., Physics, University of Madras, India, 1972
M.S., Physics, (optics & Spectroscopy), Annamalai University, India, 1974
M.S., Bio Eng., Indian Institute of Technology, Madras, 1980
Ph.D., Bio Eng., Indian Institute of Technology, Madras, 1983
Postdoc, Bio Eng., University of Washington, Seattle, WA, 1984-1987
Biography

Prof. Ammasi Periasamy received his M.S. in Physics (Annamalai University, Tamil Nadu) and M.S./Ph.D. in Biomedical engineering (Imaging) from the Indian Institute of Technology, Madras, India. Postdoctoral training in Biomedical Imaging (light microscopy) was at the University of Washington, Seattle. Prof. Periasamy worked at the University of North Carolina at Chapel Hill and he developed fluorescence lifetime imaging microscopy (FLIM) for measuring the oscillations in cytosolic and nuclear free calcium in single intact living cells. Prof. Periasamy joined the University of Virginia and is currently working as a Professor of Biology and Biomedical Engineering.

Prof. Periasamy is an internationally recognized expert in advanced microscopy techniques, particularly in the area of molecular imaging in living cells, tissue and animal. A key area of his research is focused on the design and development of optical methodology including advanced light microscopy techniques to investigate/monitor exogenous and endogenous protein-protein interactions, intravital imaging and monitoring the physical parameters of normal versus cancer cells/tissues. Prof. Periasamy is the founder and center director of the internationally known W.M. Keck Center for Cellular Imaging (KCCI; http://www.kcci.virginia.edu/). Prof. Periasamy is one of the pioneers in the development of fluorescence lifetime imaging microscopy (FLIM) for measuring the oscillations in cytosolic and nuclear free calcium in single intact living cells. He developed a 2- and 3-color steady state, confocal, multiphoton, and FLIM based Förster resonance energy transfer (FRET) imaging system for protein localization in living specimens. He has published over 100 articles in refereed journals and book chapters. http://kcci.virginia.edu/peri-publications He has given more than 100 invited lectures nationally and internationally. Prof. Periasamy has edited three books, series book editor on cellular and clinical imaging (6 books), http://kcci.virginia.edu/publications/books Chairperson in organizing an annual International conference on Multiphoton Microscopy in the Biomedical Sciences through SPIE (since 2001) and runs a hands on training annual workshop  on FLIM & FRET Microscopy at the University of Virginia, Charlottesville during March (since 2002). http://kcci.virginia.edu/workshop Prof. Periasamy was elected “Fellow” members of the SPIE Optical Society in 2012.    

AS-BIOL High-speed and high-resolution Zeiss880 multiphoton microscopy system
Source: U.S. National Institutes of Health Office of the D
June 01, 2019 – May 31, 2021
EN-BME Dial-Modal Microscopy of Metabolic Reprogramming in Cancer
Source: U.S. NIH Institute of Biomedical Imaging & Bioengi
December 01, 2015 – November 30, 2017
AS-BIOL Cellular S-Nitrosothiol Signaling in Respiratory Biology
Source: Case Western Reserve University
April 01, 2015 – March 31, 2017
AS-BIOL Cellular S-Nitrosothiol Signaling in Respiratory Biology
Source: Case Western Reserve University
April 01, 2014 – March 31, 2015
AS-BIOL Zeiss 780 NLO High Sensitivity Multiphoton Microscopy System
Source: U.S. National Institutes of Health Office of the D
June 15, 2013 – June 14, 2014
AS-BIOL Cellular S-Nitrosothiol Signaling in Respiratory Biology
Source: Case Western Reserve University
April 01, 2013 – March 31, 2014
AS-BIOL Cellular S-Nitrosothiol Signaling in Respiratory Biology
Source: Case Western Reserve University
January 23, 2013 – March 31, 2013
BIOL 4920: Independent Research in Biology
Credits: 2
Independent research for qualified undergraduates under the direction of a faculty member within the Biology Department. Prerequisite: Instructor Permission
BIOL 5070: Practical Aspects of Light Microscopy in the Biological Sciences
Credits: 3
Practical usage of various microscopy imaging methodologies to study the morphology and cellular function in various biological systems from single cell to single molecule in cells and tissues. Topics include basics theory of microscopy, imaging and image analysis to solve various biological questions, fluorophore labeling, technical and hands on training on various microscopy techniques applied in different biological and biomedical investigations. Lectures, discussion, student presentations and laboratory.
BIOL 7994: Independent Study in Biology
Credits: 1–4
This course is for graduate students participating in graded, graduate-level courses offered at MLBS during summer sessions. Students enroll in this course during the fall semester following completion of the MLBS summer course. Credits earned are the same as the number of credits designated for the MLBS course. Upon completion of the course, the instructor of record provides a grade and a written evaluation of each student's work in the course